Best Colon Cleansers of 2022: Top Supplements to Cleanse Your Colon

Digestive waste or toxins in your digestive tract can be hazardous for your health; if it accumulates in excess, it can cause a wide range of health conditions, including high blood pressure, arthritis, indigestion, and irritable bowel syndrome.

Science suggests that colon cleansing can remove this toxic waste from the body, leading to better digestion, weight loss, improved energy, and better thinking. But what does colon cleansing mean?

Colon cleansing is also known as colonic hydrotherapy or colon irrigation. It involves flushing the large intestine with fluids to eliminate waste. This practice dates back centuries, but today we have more efficient and safe colon cleansing agents than ever before.

Although your body’s colon naturally cleanses itself, colon cleansers support the body’s detoxification process, remove impacted waste, and support better digestion.

Today, you’ll find numerous colon cleansing supplements; some are the powdered ones, while others are available as liquid supplements. On the other hand, in extreme cases, colon cleansing is also practiced in the hospital setting by a colonic hygienist.

To make things simple, we will cover the top colon cleansing supplements of 2022.

The Top 19 Best Colon Cleansing Supplements in 2022

After thorough research and in-depth analysis, we ranked the following supplements as the best colon cleansing formulas of 2022.

  • Peak BioBoost
  • ColonBroom
  • Microbiome Plus+ Colon Cleanse
  • VitaBalance Colon Detox Plus
  • Herbal Power Flush
  • Herbal Parasite Garden
  • Primal Harvest Primal Gut Restore
  • COLOBOTAN Herbal Colon Cleansing Formula
  • Perfect Origins Perfect Flush
  • SynoGut
  • GoDaily Prebiotic
  • Intensive Colon Cleanse
  • UMZU zuPoo
  • Global Healing Oxy-Powder
  • Inno Supps Inno Cleanse
  • Primal Harvest Primal Total Cleanse
  • BioSchwartz Colon Detox Cleanse
  • Cor-Vital Coffee Enema Kit
  • Dr. Tobias Colon Cleanse

Peak BioBoost


Peak BioBoost is a powdered formula that easily mixes in your coffee or any other beverage of your choice. It features all-natural ingredients to promote regular bowel movements, boost energy, soften hard stool, and support digestion in multiple ways.

The ingredients that make this formula unique and effective include xylooligosaccharides (XOS), inulin, oat fiber, magnesium citrate, fructooligosaccharides (FOS), and probiotic bacteria. These ingredients are backed with scientific evidence and clinically tested to support colon cleansing.



If you are looking for the best supplement to relieve constipation and bloating, then ColonBroom is just for you. It uses natural ingredients, including psyllium husk, minerals, herbs, and plant extracts, to reduce bloating, increase energy, relieve constipation, cure diarrhea, and support normal blood pressure and weight loss.

The company claims that ColonBroom is a safe and effective formula that lets you poop like a winner and lose weight efficiently.

Microbiome Plus+ Colon Cleanse


Microbiome Plus+ Colon Cleanse is for those looking for a colon cleanser with a detoxifier. This supplement balances bacteria in your gut to reduce the risk of infections, and the fiber content and laxative in this formula help relieve constipation and gas. Along with this, it also boosts energy, reduces inflammation, enhances digestive health, and supports metabolic functions of the body.

Some of the ingredients added in this formula include fennel seed powder, ginger root powder, rhubarb root powder, licorice root extract, cayenne pepper, cascara sagrada bark powder, oat fiber, and senna leaf.

VitaBalance Colon Detox Plus


VitaBalance Colon Detox Plus is a 15-day colon cleanse formula to support the healthy digestive tract and natural body functions. It contains prebiotics, probiotics, and calcium to support healthy gut flora.

Essential ingredients added in this supplement include psyllium, lactobacillus acidophilus, alfalfa leaf, gentian, aloe vera, cascara sagrada, rhubarb, and buckthorn. Priced at $ 24.80, it is one of the best value options on our list.

Herbal Power Flush


Herbal Power Flush is a 100% plant-based and a vegan-friendly blend of dietary fiber, herbs, and digestive enzymes that promote regular bowel movements, feed healthy gut flora, support healthy hormonal balance, and clear excess waste from the colon.

It also promotes healthy transit time, meaning the food stays longer in the large intestine for maximum absorption of nutrients and metabolites.

Priced at $ 49, one capsule of Herbal Power Flush each day can permanently eliminate constipation.

Herbal Parasite Guardian


Herbal Parasite Guardian is a pricier option on this list; however, it’s worth buying due to its beneficial effects. It is a supplement from BiOptimizers that features a blend of 13 herbs and five digestive enzymes created to eliminate parasites, combat fungal infections and expel viruses from the body.

The company claims that this colon cleansing supplement inhibits harmful bacteria, breaks biofilm, soothes gut lining, increases mucus, supports healthy gut immune response, and promotes healthy gut flora.

Primal Harvest Primal Gut Restore


Primal Harvest Primal Gut Restore is marketed as the complete approach to gut health. As per the manufacturers, their formula supports long-lasting health, strengthens the gut lining, treats leaky gut, and improves digestion by reducing harmful bacteria in the gut.

Each formula serving offers 100 mg of xylooligosaccharides, prebiotics, 3 billion CFU of B. longum BB536 probiotics, and 1000mg of CoreBiome tributyrin to give you perfect poops regularly.

COLOBOTAN Herbal Colon Cleansing Formula


COLOBOTAN Herbal Colon Cleansing formula is an effective supplement from Dinosaur Nutrition. It is formulated in an FDA-approved and GMP-certified facility to ensure safety, high quality, and potency.

COLOBOTAN contains essential ingredients such as psyllium husk, probiotic bacteria, alfalfa, goldenseal root, gentian, rhubarb, aloe vera, cascara sagrada, buckthorn, and bentonite to help restore healthy bowel function and promote detoxification of the gut for optimal digestion.

Perfect Origins Perfect Flush


Perfect Flush features ten natural ingredients to dislodge and clean around 20 pounds of impacted poop from your colon. This supplement detoxifies your colon, supports a healthy digestive system, relieves constipation, and promotes weight loss.

The key ingredients that support all these benefits include glucomannan, prune powder, psyllium, and aloe vera; these ingredients let you enjoy a perfect flush of waste each day.



SynoGut features natural and effective ingredients added in precise amounts to support a healthy digestive system. The formula is packed with fiber that promotes easy passage of food in the gastrointestinal tract. The stool softeners let you get relief from toxin waste and irregular bowels, and the probiotics work to balance gut health.

As per the company, this formula is rich in natural ingredients, including black walnut, psyllium husk, bentonite clay, prune, flaxseed, aloe vera, and L-acidophilus.

GoDaily Prebiotic


GoDaily Prebiotic tackles the root cause of constipation and IBS. It works with the help of prebiotics and six essential nutrients that feed the probiotics in your gut to support digestion and relieve constipation.

According to the manufacturing company, this formula adds six Japanese nutrients: Jerusalem artichoke, chios mastic, FOS, nopal powder, oat fiber, and psyllium husk.

Intensive Colon Cleanse


Natural Health Source Intensive Colon Cleanse formula is a ten-day cleanse formula to revitalize your colon and relieve inflammation. This 100% natural herbal remedy offers detoxification, constipation relief, and weight loss.

The company claims that the Intensive Colon Cleanse supplement contains the best quality ingredients, including acacia gum, psyllium husk, apple pectin, senna leaf extract, and brown rice fiber to maximize digestive health.

Top Rated Colon Cleansing Supplement On Amazon

We also researched a few colon cleansing formulas available on Amazon, and out of those, we have compiled the following top-rated and effective supplements for you.

UMZU zuPoo


UMZU zuPoo is a top-rated colon cleanser that naturally flushes out waste and improves gut health. The company claims that it can decrease bloating, improve digestion and reduce belly load.

Backed by scientific research and developed by a chemist, the formula contains natural and high-quality ingredients, including cascara sagrada, bentonite clay, cayenne pepper extract, aloe forex, and milk thistle.

Global Healing Oxy-Powder


Global Healing Oxy-Powder is a colon cleanse and detox formula that aids weight loss, constipation relief in adults, and bloating relief in women and men. With the help of ozone-oxygenated magnesium and citric acid, it quickly detoxifies your gut while you sleep.

Furthermore, it is an entirely safe, vegan-friendly, non-GMO, and gluten-free formula.

Inno Supps Inno Cleanse


Inno Cleanse is a blend of potent herbs including Cascara Sagrada, fennel seed, cape aloe, licorice, cayenne pepper, buckthorn bark powder, milk thistle, and bentonite to regularize bowel movement, reduce abdominal pain, decrease bloating, detoxify the gastrointestinal tract, flush out pounds of waste, and cleanse the digestive system.

Primal Harvest Primal Total Cleanse


Primal Total Cleanse from Primal Harvest is a natural colon cleansing formula that effectively and gently detoxifies your body. It supports the liver, kidney, and colon health, helps metabolism, decreases water retention, reduces bloating, improves digestion, and supports weight loss.

Key ingredients supporting these functions are senna leaf, flaxseed, acai berry fruit, licorice root, lactobacillus acidophilus, fennel seeds, and cayenne fruit.

BioSchwartz Colon Detox Cleanse


Colon Detox Cleanse is a popular and efficient colon cleansing supplement that uses natural laxatives and probiotics to give your body a 15-day, fast-acting cleanse and constipation relief.

This formula is designed to boost weight loss, alleviate bloating, eliminate waste, support digestion, and boost immunity. Key ingredients include senna leaves, ginger, flax seeds, cascara sagrada, black walnut hull, and slippery elm bark.

Cor-Vital Coffee Enema Kit


Coffee enema is one of the favored, and proven types of colon cleanse used in alternative medicine. Cor-Vital Coffee Enema Kit is high quality and mess-free kit that provides everything you need to detox your body.

On unboxing, you will get an enema bucket, 1 lb enema coffee, soft vinyl enema tube, and red tube with instructions on using the coffee enema kit. Priced at $ 59.97, it is one of the top options available today.

Dr. Tobias Colon Cleanse


Dr. Tobias Colon Cleanse formula is the most cost-friendly option on our list, at just $16, and it uses high-quality ingredients, including senna leaf, cascara sagrada, psyllium husk powder, and aloe vera gel.

The company claims that this supplement supports healthy bowel movements, improves digestive health, and cleanses your body from toxins and waste within 14 days.

How We Ranked Best Colon Cleansing Supplements For 2022

There are thousands of colon cleansing supplements available in the market, and all claim to be natural, effective, and safe for your body. However, many of these don’t work.

Picking the right colon cleansing supplement is challenging; therefore, we have ranked the top colon cleansing formulas based on valuable ranking factors.

Science-Backed And Natural Ingredients

We rank the supplements that contain natural ingredients backed by scientific research or clinical trials. For instance, science proves the efficiency of fiber and probiotics to balance your gut microbiome and support healthy digestion; thus, you will find colon cleansing supplements packed with fiber and probiotics on our list.

Clinically Effective Dosages

As per scientific evidence, most ingredients work if consumed in standard dosages; however, some supplements contain science-backed ingredients at low doses that are ineffective in detoxifying your body.

Thus, we only consider supplements that contain scientifically proven ingredients at clinically effective dosages.

Honest Advertised Benefits

Some supplement manufacturing companies make big claims to market their products; they make unrealistic claims that the colon cleansing supplement can help you lose 30 pounds of weight and eliminate the risk of colon cancer. Unfortunately, these supplements never work. We only prefer the companies that advertise their formula with realistic claims and benefits so the consumer may expect the truth.

Manufacturer Transparency

We rank the companies that are transparent with their customers. We believe that users have the right to know all the ingredients added to the supplements with their dosages.

If the manufacturer doesn’t disclose the list of ingredients or their dosages, they might be using low-quality or hazardous components. Thus, we do not rank them on our list.

Customer Reviews

For ranking colon cleansers, we also checked customer testimonials. Customer reviews tell how the supplement works for most users and the side effects it may cause. Although the results of colon cleansing formulas vary with different individuals, we get a general overview of the supplement by checking customer reviews.

Price And Value

Supplements vary in cost. You can get a colon cleanser at $16 or buy a colon cleansing supplement at $ 70. We believe that whatever the supplement’s price, it should offer optimum benefits to the consumers. Thus, we include those supplements that provide a good value for the money.

Ease Of Use

There is a wide range of colon cleansers available in the market. Some colon cleansers require you to consume just two capsules per day, while others require mixing the powdered formula in a cup of coffee. On the other hand, a few colon cleansers need you to insert a tube into your body. Whatever the requirements, we only prefer supplements that are easy to use and backed with simple instructions.

Money-Back Guarantee

Most reputed companies offer zero-risk purchases with a money-back guarantee and return policy. Not all supplements can work for everyone; thus, if the colon cleansing supplement does not work for you, you should be able to get your money back.

We used these factors to rank products in our best colon cleansing supplements list for 2022.

Colon Cleansers Benefits

There is a lack of scientific evidence linked to the benefits of colon cleansing, but some of the obvious benefits include:

Cleanse The Colon

Our body naturally eliminates the waste, but some remain impacted in the colon most of the time. Colon cleansers help you flush out the impacted waste from the body and aid in removing toxins that your body struggles to release naturally.

Aids Hydration

Most colon cleansers increase your water consumption, thus aiding in rehydration. On the other hand, colon cleanser or colonic hydrotherapy includes passing a large amount of water – 16 gallons through your colon. Some water gets absorbed in the body, thus hydrating your cells.

Revitalize The Digestive System

The removal of toxins and waste from the gut revitalizes the digestive tract and improves digestion. After a colon cleanses, your colon gets rid of the excrement, boosting the absorption of nutrients from the food.

Stimulate Reflex Points

You have reflex points all over your body, and colon cleansing stimulates the reflex points, benefiting the other parts of the body.

Strengthen Colon Muscles

Impacted waste can harden your colon and impede its function. When the impacted waste is removed from the colon, it strengthens your colonic muscles and improves function.

Regulates PH Balance

Waste and toxins are acidic that disturb the overall pH of your body. Colon cleansing regulates your body’s pH and supports the healthy functioning of all organ systems.

Help In Weight Loss

Food items that are poor in fiber slow down the procedure of food digestion, producing excess mucus that sticks to the intestine lining. This mucous, along with extra pounds of fecal matter, increases weight.

Colon cleansing removes the waste and contains fiber that speeds up digestion. Thus, it is true that colon cleansers can aid in a significant reduction of weight.

Improves Concentration, Focus, And Energy

An unbalanced diet and ineffective vitamins and minerals absorption cause an individual to stay distracted and lose concentration. Cleansing the colon and detoxification improve absorption of essential nutrients, thus enhancing the body’s focus, concentration, and energy levels.

How Colon Cleansing Works?

Colon cleansing is a procedure used to detoxify the body, eliminate waste from the large intestine and reduce the risk of colon disease. Colon cleanse is done in multiple ways, including:

Colonic Irrigation

Colonic irrigation or colonic hydration is a process in which a tube is inserted into the rectum, and water or a mixture of water, herbs, coffee, and other natural ingredients flows through the tube into your body to flush the toxin and waste out of the body.

Colon Cleansing Supplements

Colon cleansing supplements contain fiber, natural laxatives, and other essential ingredients to support natural detoxification and waste removal out of the body.

Other colon cleansing therapies include herbal colonic irrigation, enemas, and others.

What Does Science Say About Colon Cleansers?

Colon cleansers offer numerous benefits but are they backed by scientific evidence? Let’s review a few studies linked to colon cleansers.

As per Healthline, you can boost colon health by adopting simple things at home. These include:

  • Water flush
  • Saltwater flush
  • High fiber diet
  • Resistant starches
  • Juices and smoothies
  • Herbal teas
  • Probiotics

A study conducted in 2010 suggests that saltwater can cleanse the colon when combined with some yoga poses. For this, mix two teaspoons of sea salt or Himalayan salt in lukewarm water and drink it two times per day on an empty stomach.

Another study in 2015 concluded that juices and smoothies could help with colon cleansing. Fruit juices rich in vitamin C are best for colon and digestive health. Also, resistant starches in plant foods such as legumes, potatoes, and grains promote a healthy colon by boosting beneficial gut microflora. A review of 2013 also concluded that resistant starches reduce the risk of colon cancer.

Moreover, laxative herbs like aloe vera, psyllium, marshmallow root, and slippery elm that you get from many colon cleansing supplements help with constipation.

Fiber is also considered a remedy for colon cleanse. Fiber-rich foods speed up digestion, aiding in the quick removal of waste from the body. Fiber build-up a gel-like paste in the gastrointestinal tract, forcefully passing waste out of your body and accelerating the detoxification process. Various studies also relate a fiber-rich diet to a reduced risk of colon cancer.

You can also benefit from colonic irrigation if you have irritable bowel syndrome. A study conducted in 2016 evaluated the efficiency of colonic irrigation for irritable bowel syndrome. This study concluded that colonic irrigation reduced abdominal pain, constipation, and diarrhea in patients with IBS, and patients reported regular bowel movements and reduction of symptoms.

A study published in Gastrointestinal Radiology in 1982 suggests that a blend of bisacodyl, anthraquinone glycosides (cascara), and sodium picosulfate promotes colon cleanse in 52 to 80% of participants. The same procedure repeated with tap water enema reported 96% positive results.

A 2014 study suggests that herbal teas are also linked with colon health and reduce the risk of colon cancer. On the other hand, the same study proved that iced coffee is associated with rectal cancer risk.

As per Cedars-Sinai, some of the most proven ways to improve colon health are: avoiding tobacco, limiting red meat and alcohol consumption, and exercising at least three times per week.

Overall, colon cleanses help remove waste from the colon; however, due to limited scientific evidence, most doctors recommend a healthy diet and exercise for cleansing the colon.

Colon Cleansers Side Effects

Most colon cleanser supplements are manufactured using Generally Recognized As Safe (GRAS) ingredients, which means these supplements are safe to use by healthy individuals. You must consume the colon cleansing supplement in recommended dosages and do not exceed the dose of the formulas.

Unfortunately, many colon cleansers are linked with side effects, particularly if the frequency of their use is increased. Some of the reported side effects include:

  • Vomiting
  • Nausea
  • Dehydration
  • Cramping
  • Electrolyte imbalances
  • Dizziness

These symptoms are linked with more severe results, including perforation in the colon, heart failure, digestive tract damage, and chronic constipation.

Therefore, always consult an expert doctor before using any colon cleanser.

Frequently Asked Questions About Colon Cleansers

Below, we have answered a few of people’s most common questions about colon cleansers.

Q. What is the colon?

A: The colon is the longest part of the large intestine; it removes water and nutrients from the partially digested food that reaches your large intestine.

Q. What is an enema?

A: Enema is a procedure in which gas or liquid is injected into the rectum to flush out the contents or introduce drugs for x-ray imaging.

Q. What is colonic hydrotherapy?

A: Colon hydrotherapy features flushing out of waste from the colon with the help of a large amount of water. Generally, a tube is inserted into the body, and water flows through this tube to remove impacted waste from the body.

Q. How much time does the colon hydrotherapy procedure take?

A: Colon hydrotherapy usually takes around 30 to 60 minutes.

Q. How can I know whether I need a colon to cleanse or not?

A: If you usually struggle to pass bowel movements or suffer from constipation and digestive issues, you may require a colon cleanse. Also, if your diet includes frequent consumption of tea, coffee, alcohol, sugar, tobacco, or toxins, you may need a colon cleanse.

However, always consult a doctor before going for a colon cleanse.

Q. What are the benefits of colon cleansing?

A: The obvious benefit is getting rid of impacted waste and toxins from your body. But people also experience improved digestion, better bowel movements, improved focus and concentration, higher energy levels, and less bloating after colon cleansing.

Q. Is colon cleanse a painful procedure?

A: Generally, a colon cleanse is painless, but initially, you may feel cramping or slight pain. Also, colon cleanse can cause side effects such as vomiting, diarrhea, dehydration, and electrolyte imbalances.

Q. Does health insurance cover colon hydrotherapy?

A: Colon hydrotherapy is usually not covered in insurance.

Q. Is there any protocol to follow before colon cleansing?

A: Most experts do not recommend anything special to prepare for colonic therapy. However, some recommend avoiding heavy meals and drinking a lot before the appointment.

Q. Is there any protocol to be followed after colonic therapy?

A: After colonic therapy, you must drink water and replenish your electrolytes to decrease the chances of dehydration.

Q. Can I cleanse my colon at home?

A: Yes, many simple to use home kits are available for colon cleanse. Also, you can cleanse your colon by consuming a high fiber diet, juices and smoothies, resistant starches, and with the help of water flush. These all are at-home colon cleansing methods.

Q. Can I go for a colon cleanse during my period days?

Yes! Some people recommend going for colon cleanse on period days because your body is already removing waste out of the body. Some people believe that colon cleansing therapy relieves cramping, abdominal pressure, and bloating associated with the period.

Q. Which colon cleansing supplement is the best?

A: Out of hundreds of colon cleansers available in the market, the above supplements on our list of top 19 colon cleansing formulas are best to use.

The Top 19 Best Colon Cleansing Supplements in 2022 Final Thoughts

Even though your body naturally removes toxins and waste, colon cleansers are in demand now. Colon cleanser supports the body’s natural detoxification process, removes impacted waste, and improves digestion. Some people prefer colon cleansing supplements, while others undergo colonic hydrotherapy to remove waste from the body.

Whichever procedure you choose, we recommend you consult a doctor before consuming any colon cleansing supplement or undergoing colonic therapy. If you are confused about which colon cleanser to select, view our list of the top 19 colon cleansing supplements of 2022.

Note that any guidelines or information mentioned in this article is not an alternative to medical advice from a certified physician. Ensure to consult a professional before making any purchase; if you are currently suffering from any disease or taking medications, always refer to your doctor before following any colon cleansing method.

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